Published:  Jun 28, 2016DOI: 10.7324/JAPS.2016.60626
Streptomyces from rare ecosystems is the promising source for secondary metabolites exhibiting diverse biological activities. The present study reports the antioxidant activity and antimicrobial activity against biofilm forming bacteria by the pigment produced from Desert soil Streptomyces sp. D25. Crude pigment from the Streptomyces sp D25 was produced by agar surface fermentation using yeast extract malt extract agar and extracted using ethyl acetate. Antioxidant activity of pigment was tested at 100-500µg/ml concentration by DPPH and nitric acid scavenging assay. Antimicrobial activity against the biofilm forming bacteria was tested by disc diffusion method. The Streptomyces pigment showed 35.63% and 96.19% free radical scavenging activity in DPPH assay and nitric oxide assay, respectively. The results of radical scavenging activity of pigment in DPPH and nitric oxide assay showed its antioxidant potential. In antimicrobial assay, the pigment showed 10-20 mm inhibition against biofilm forming bacteria at 25µg/ml. Further in vivo studies on this Streptomyces pigment pave the way for its biomedical applications.
Radhakrishnan M, Gopikrishnan V, Vijayalakshmi G, Kumar V. In vitro antioxidant activity and antimicrobial activity against biofilm forming bacteria by the pigment from Desert soil Streptomyces sp D25. J App Pharm Sci, 2016; 6 (06): 148-150.
331 Absract views 27 PDF Downloads 358 Total views
Antifungal activity of 3-methylcarbazoles from Streptomyces sp. LJK109; an endophyte in Alpinia galangalThongchai Taechowisan, Srisakul Chanaphat, Wanwikar Ruensamran, Waya S. Phutdhawong
Evaluation of phytoconstituents, nephro-protective and antioxidant activities of Clitoria ternateaK.Sarumathy, M.S.Dhana Rajan, T.Vijay, J.Jayakanthi