Research Article | Volume: 6, Issue: 5, May, 2016

Physical, Mechanical and Antimicrobial Evaluations of Physically Crosslinked PVA/Chitosan Hydrogels Containing Nanoparticles

Ahmed Saad Montaser   

Open Access   

Published:  May 28, 2016

DOI: 10.7324/JAPS.2016.60501
Abstract

Chitosan/montmorillonite (MMT) and Poly vinyl Alcohol (PVA) / Silver nanoparticles (AgNPs) nanocomposites were prepared and formed hydrogel membranes using freeze thawing technique. The properties of the prepared hydrogels were investigated and compared to hydrogel membranes in presence and absence of nanometals. The physical behavior, mechanical properties and antibacterial activity was examined. Also the surface morphology monitored using scanning electron microscope. Antimicrobial activity against bacteria and yeast was also examined. The obtained results showed positive effect of nanometals especially AgNPs on swelling percent on the other hand tensile strength were combined by presence of MMT nanoparticles. The surface morphology showed homogenous images for all samples except samples containing MMT. All prepared samples containing nanoparticles showed antibacterial activity especially hydrogel membranes containing AgNPs.


Keyword:     PVA Chitosan Freeze-thawing AgNPs MMT hydrogel Antibacterial.


Citation:

Montaser AS. Physical, Mechanical and Antimicrobial Evaluations of Physically Crosslinked PVA/Chitosan Hydrogels Containing Nanoparticles. J App Pharm Sci, 2016; 6 (05): 001-006.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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