Research Article | Volume: 6, Issue: 1, January, 2016

Antioxidant and Immunotropic Properties of some Lithium Salts

Evgenii PlotnikovOlesya VoronovaWolfgang LinertDmitrii MartemianovElena KorotkovaElena DorozhkoAnna AstashkinaIrina MartemianovaSvetlana IvanovaNikolay Bokhan   

Open Access   

Published:  Jan 26, 2016

DOI: 10.7324/JAPS.2016.600115

Objective: The antioxidant activity and immuno-tropic effects of lithium glutamate, lithium salicylate, lithium benzoate and lithium lactate have been investigated in this work, as a base for new psychotropic medicines. Methods: The antioxidant properties were studied by the voltammetric method. Phagocytic activity of neutrophilic leucocytes and the reaction of blastic transformation of lymphocytes were used as test for assessments of influence of the lithium compounds on the immune cells of human blood. Results: It was revealed absence of toxic action on human blood cells for all tested substances. Lithium benzoate showed the most significant stimulating influence on lymphocytes. Glutamate and benzoate lithium expressed scavenging activity vs oxygen radicals. Salicylate and benzoate lithium revealed significant phagocytosis stimulation effects. Conclusion: Investigated lithium salts expressed antioxidant activity and immunotropic effects, all investigated substance are of interest in medical application for mental diseases and comorbid pathology treatment.

Keyword:     Antioxidant Activity immunotropic effects voltammetry phagocytosis RBTL mental diseases lithium glutamate lithium salicylate lithium benzoate lithium lactate.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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