Research Article | Volume: 5, Supplement: 3, November, 2015

In vitro Evaluation of Antioxidant properties of Hodgsonia heteroclita (Cucurbitaceae) fruit

Silu Basumatary Ajit Kumar Das Raaman Nanjian Gauri Dutt Sharma   

Open Access   

Published:  Nov 12, 2015

DOI: 10.7324/JAPS.2015.510.S14

Hodgsonia heteroclita fruits have been used as traditional drug for antidiabetic in Western Assam, India. The study aimed to investigate antioxidant activity of methanolic fruit extract of H. heteroclita. The antioxidant activity of fruit was determined by employing different In vitro assays such as DPPH•, ABTS•+ radical scavenging capacities and reducing power assay-phosphomolybdenum. The results of the present study revealed that the methanol fruit extract exhibited strong scavenging effect on DPPH (2,2-diphenyl-1picrylhydrazyl) with IC50 =20.98±0.17 than ABTS [2,2´-azino-bis(3-ethylbenzothiazoline-6-sulphonate) with IC50 =28.58±0.42. The reducing power phosphomolybdenum assay showed inhibition with ascorbic acid as standard. Fruit extract exhibit free radical scavenging and reducing properties which might constitute an important source of natural antioxidants. Thus the study indicates that this plant has a potential to be used as an antioxidant and also can be used to prevent diseases directly linked to oxidative stress.

Keyword:     Hodgsonia heteroclitaantioxidant activityDPPHABTS and phosphomolybdenum.


Silu Basumatary, Ajit Kumar Das, Raaman Nanjian, Gauri Dutt Sharma. In vitro Evaluation of Antioxidant properties of Hodgsonia heteroclita (Cucurbitaceae) fruit. J App Pharm Sci, 2015; 5 (Suppl 3): 080-083.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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