Research Article | Volume: 5, Issue: 10, October, 2015

Degradation of cefdinir from pharmaceutical waste water using immobilized Candida sp. SMN04 and biofilm formed on gravels

Adikesavan Selvi Monidipa Banerjee Nilanjana Das   

Open Access   

Published:  Oct 28, 2015

DOI: 10.7324/JAPS.2015.501013

Cefdinir being a semi-synthetic third generation cephalosporin antibiotic is considered as an emerging pollutant which demands removal from environment. Degradation of cefdinir by yeast Candida sp. SMN04 immobilized on various single and hybrid matrices was investigated using entrapment method. The biofilm forming ability of Candida sp. was evaluated by crystal violet staining assay and the formed biofilm was monitored by SEM and AFM analysis. The amount of exopolysaccharides (EPS) produced by Candida sp. was quantified and characterized by FTIR, HPLC and TGA analysis respectively. Cefdinir degradation from pharmaceutical wastewater was found to be 96.6% and 92.2% by PVA-alginate immobilized yeas tand yeast biofilm formed on gravels over a period of 48 h in batch mode. Effectiveness of the process was also tested involving continuous-flow column studies. This is the first successful attempt on cefdinir degradation using immobilized yeast cells and yeast biofilm on solid substrate.

Keyword:     Biofilm CefdinirDegradation Immobilization Pharmaceutical wastewater.


Adikesavan Selvi, Monidipa Banerjee, Nilanjana Das. Degradation of cefdinir from pharmaceutical wastewater using immobilized Candida sp. SMN04 and biofilm formed on gravels. J App Pharm Sci, 2015; 5 (10): 073-079.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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