Research Article | Volume: 5, Issue: 10, October, 2015

Chemical Composition and in vitro Antibacterial Activity of the Essential Oils of the Leaves, Resin and Stem-Barks of Dacryodes edulis (G. Don) H. J Lam growing in Cameroon on Diarrhea Associated Strains

Sara Honorine RIWOM Florentine M-C NDOYE FOE Maximilienne Ascension NYEGUE Reskingjoe AMBE WANKI Steve VOUNDI Olugu François-Xavier ETOA   

Open Access   

Published:  Oct 28, 2015

DOI: 10.7324/JAPS.2015.501002

The aim of this work was to determine the chemical profile and assess in vitro the antibacterial activity of the leaves, resin and stem-barks of Dacryodes edulis. The essential oils were analyzed simultaneously by Gas Chromatography and Gas Chromatography coupled to Mass Spectrometry. Agar diffusion well and microdilution methods were used to assay the antibacterial activity. The resin essential oil contained p-cymene (30.32%), α-thujene (28.58%), α-phellandrene (27.14%) and β-phellandrene (10.16%) as the main components; the stem-barks essential oil had as abundant components p-cymene (35.14%), trans-carveol (22.60%), α-thujene (14.86%), β-phellandrene (8.65%) and β-elemene (5.22%). The leaves essential oil was distinct with elemol (29.22%), caryophyllene oxide (15.26%), trans-carveol (11.80%) and spathulenol (6.28%) as major components. The leaves essential oil was the most active with MIC and MBC value of 18.75 mg/mL on B. cereus; the most susceptible strain. The stem-barks essential oil had a MIC of 50 mg/mL and MBC of 100 mg/mL on all the strains meanwhile the resin essential oil had a bacteriostatic effect at 200 mg/mL. Based on these results, it emanates that the essential oils of D. edulis represent a potential source of antibacterial substances.

Keyword:     Dacryodes edulis Essential oil Chemical composition Antibacterial activity Diarrhea.


Sara Honorine Riwom, Florentine Marie chantal Ndoyé Foe, Maximilienne Ascension Nyegue, Reskingjoe Ambe Wanki, François-Xavier Etoa. Chemical Composition and in Vitro Antibacterial Activity of the Essential Oils of the Leaves, Resin and Stem-Barks of Dacryodes Edulis (G. Don) H. J Lamgrowing in Cameroon on Diarrhea Associated Strains. J App Pharm Sci, 2015; 5 (10): 006-011.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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