Research Article | Volume: 5, Issue: 8, August, 2015

Evaluation of Anti-oxidant and Anti-diabetic Activity of Flower Extract of Clitoria ternatea L

Manivannan Rajamanickam Prabakaran Kalaivanan Ilayaraja Sivagnanam   

Open Access   

Published:  Aug 28, 2015

DOI: 10.7324/JAPS.2015.50820
Abstract

Clitoria ternatea belonging to the family Fabaceae, commonly known as Butterfly pea. A wide range of secondary metabolites including triterpenoids, flavonol glycosides, anthocyanins and steroids were isolated from Clitoria ternatea Linn. GC-MS analyses of CHCl3 and EtOAc fractions were performed on Gas Chromatography with mass spectrometer. The aim of the present study was to evaluate the radical scavenging ability, using the stable radical DPPH and anti-diabetic activity in alloxan induced diabetes in albino rats was evaluated from the flowers extract of Clitoria ternatea. The blood glucose level in the different groups was assayed and biochemical parameters were assessed to support the proposed hypothesis. During the experimental period, body weight of all the rats was determined at regular intervals of time. The serum glucose lowering activity was compared with glibenclamide, a standard hypoglycemic drug.


Keyword:     Clitoria ternatea GC-MS analysis blood glucose level biochemical estimation.


Citation:

Manivannan Rajamanickam, Prabakaran Kalaivanan, Ilayaraja Sivagnanam. Evaluation of Anti-oxidant and Anti-diabetic Activity of Flower Extract of Clitoria ternatea L. J App Pharm Sci, 2015; 5 (08): 131-138.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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