Research Article | Volume: 5, Issue: 6, June, 2015

Phytochemical screening and evaluation of analgesic and antiinflammatory activities of Phaseolus vulgaris linn., seeds in rodents

M. R. Pradeepkumar Shrinivas D. Joshi V. H. Kulkarni Chetan Savant   

Open Access   

Published:  Jun 27, 2015

DOI: 10.7324/JAPS.2015.50610
Abstract

With an objective of developing some novel analgesic and antiinflammatory natural agents with fast acting and low toxicity profile herein, the different extracts of Phaseolus vulgaris (Linn) seeds were evaluated for analgesic and antiinflammatory activities using glacial acetic acid induced writhing and carrageenan induced rat paw oedema method respectively. For screening of the extracts for analgesic and antiinflammatory activities aspirin and diclofenac were used as standard drugs respectively. Petroleum ether extract exhibited significant analgesic and antiinflammatory activities. The petroleum ether extract can be considered as a potential candidate for analgesic and antiinflammatory activities. The presence of steroids and flavonoids in petroleum ether extract of Phaseolus vulgaris Linn., seeds could be attributed for the analgesic and antiinflammatory activities.


Keyword:     Analgesic Antiinflammatory Phaseolus vulgaris Linn. seeds carrageenan glacial acetic acid.


Citation:

M. R. Pradeepkumar, Shrinivas D. Joshi, V. H. Kulkarni, Chetan Savant., Phytochemical screening and evaluation of analgesic and antiinflammatory activities of Phaseolus vulgaris linn., seeds in rodents. J App Pharm Sci, 2015; 5 (06): 066-069.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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