Short Communication | Volume: 5, Issue: 1, January, 2015

Piceatanol: Anti-Cancer Compound From Gewang Seed Extract

Leny Heliawati ,  Agus Kardinan, Tri Mayanti,  Roekmi-ati Tjokronegoro   
Leny Heliawati1 & 2, Agus Kardinan3,Tri Mayanti1, Roekmi-ati Tjokronegoro1

1Graduate School, Padjadjaran University, Bandung, West Java, Indonesia.

2Pakuan University, Bogor, West Java, Indonesia.

3Indonesian Spice and Medicinal Crops Research Institute, Indonesia

Open Access   

Published:  Jan 30, 2015

DOI: 10.7324/JAPS.2015.50119
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Abstract

Piceatannol (Compound 1), brownish white solids compound, is a stilbene compound has been isolated from methanol seeds extract of Corypha utan Lamk. Isolation and purification conducted by chromatographic methods. Structure elucidation deduced on the basis of spectroscopic data (UV spectrometer, FTIR, NMR and HRMS). MTT assay method of cytotoxicity activity showed that Compound 1 has a very strong cytotoxic activity against Murine leukemia P-388 cell lines with IC50 value 1.56 ppm.


Keyword:     Corypha utan Lamk Murine leukemia P-388 Cytotoxic Chromatography Piceatannol.

Citation:

Leny Heliawati, Agus Kardinan, Tri Mayanti, Roekmi-ati Tjokronegoro. Piceatanol: Anti-Cancer Compound From Gewang Seed Extract. J App Pharm Sci, 2015; 5 (01): 110-113.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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