Systemic Lupus Erythematosus (SLE) is a multisystem connective tissue disorder associated with increased predisposition to haematological malignancies. Myeloid series malignancies are rarely associated with SLE. We here report a case of Philadelphia chromosome positive chronic myeloid leukemia (CML) associated with SLE in a 36 year old Indian housewife. This is probably the first such case to be reported from India and only a handful of such cases have been reported in World literature till now. The patient presented initially with leukopenia. She was treated with imatinib with good results.
Rudrajit Paul, Jayanti Ray, Babulal Daulagajao, Rojina Choudhury, Sanjoy Bhattacharya. Systemic lupus erythematosus and chronic myeloid leukemia: mere coexistence or association? J App Pharm Sci, 2014; 4 (11): 098-100.
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The Effects of Ethanolic Extract of Vitex Doniana Stem Bark on Peripheral and Central Nervous System of Laborotory Animals
Sorafenib combination with imatinib enhances apoptotic and cell cycle arrest effects with no effect on viability and BCR-ABL expression of K-562 cells
Belal A. Al-Husein, Ahmad Al-Azayzih, Fatema S. Redha