Research Article | Volume: 4, Issue: 10, October, 2014

Chemical compositions and anti-inflammatory activities of essential oils from Aster spathulifolius and Vitex rotundifolia maxim

Chunsuk Kim Hee Jung Bu Sun Joo Lee Chang-Gu Hyun and Nam Ho Lee   

Open Access   

Published:  Oct 30, 2014

DOI: 10.7324/JAPS.2014.401003

The essential oils were prepared from Aster spathulifolius (ASE) and Vitex rotundifolia (VRE) by hydrodistillation and their chemical compositions were investigated by GC–MS. Analysis of ASE provided 15 components and eight of which were identified sesquiterpene compounds. The major components in ASE included germacrene D (35.1 %), trans-caryophyllene (15.9 %) and trans-phytol (14.9 %). On the other hand, VRE provided manoyl oxide (14.3%), α-terpineol (13.1 %) and α-pinene (10.0 %) as major ingredients. To assess the anti-inflammatory effects of the essential oils, the production of nitric oxide (NO) and tumor necrosis factor (TNF)-α were monitored using lipopolysaccharide (LPS)-activated RAW 264.7 macrophages. In this test, ASE and VRE were appeared to suppress both NO and TNF-α synthesis in dose-dependent manner. The results indicate that VRE and ASE could be useful in cosmetic applications as natural products possessing anti-inflammatory efficacy.

Keyword:     Essential oils chemical composition Aster spathulifolius Vitex rotundifolia anti-inflammation.


Chunsuk Kim, Hee Jung Bu, Sun Joo Lee, Chang-Gu Hyun and Nam Ho Lee. Chemical Compositions and Anti-inflammatory Activities of Essential Oils from Aster spathulifolius and Vitex rotundifolia Maxim. J App Pharm Sci, 2014; 4 (10): 012-015.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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