Research Article | Volume: 4, Issue: 7, July, 2014

In vitro antioxidant and antibacterial activities of two fresh water Cyanobacterial species, Oscillatoria agardhii and Anabaena sphaerica

Azza M. Abd El-Aty Amal A. Mohamed Farag A. Samhan   

Open Access   

Published:  Jul 28, 2014

DOI: 10.7324/JAPS.2014.40712

Cyanobacteria are potential sources of biologically active compounds with antiviral, antibacterial, antifungal, and anticancer activities. In the present investigation, the effect of different solvents, including methanol, acetone, and water on the total phenolic, flavonoid, antioxidant and antibacterial activities of Oscillatoria agardhii and Anabaena sphaerica extracts were evaluated. The results showed that solvents with different polarities have various effects on phenolic content and antioxidant activity. Among the tested solvents, methanolic extract of Oscillatoria agardhii showed the highest antioxidant activity as well as the highest phenolic content. Organic extracts (with methanol or acetone) of the tested species actively inhibited the growth of bacteria compared to aqueous extracts. The highest antibacterial activity was detected by acetone extract of Oscillatoria agardhii against Salmonella senftenberg. By GC-MS analysis some important heterocyclic compound were identified in both Oscillatoria agardhii and Anabaena sphaerica crude extracts. This appeared to be responsible for such excellent antioxidant and antibacterial activity together with other unidentified compounds. Further exploration of antibacterial potential of cyanobacteria can open new horizons.

Keyword:     Antibacterial activitycyanobacteria DPPH radical scavenging assay phenolic compounds volatile organic compounds.


Azza M. Abd El-Aty, Amal Amin Mohamed, Farag Samhan. In Vitro Antioxidant and Antibacterial Activities of Two Fresh Water Cyanobacterial Species, Oscillatoria agardhii and Anabaena sphaerica. J App Pharm Sci, 2014; 4 (07): 069-075.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

HTML Full Text


Article Metrics
418 Views 58 Downloads 476 Total



Related Search

By author names