Published:  Jul 28, 2014DOI: 10.7324/JAPS.2014.40712
Cyanobacteria are potential sources of biologically active compounds with antiviral, antibacterial, antifungal, and anticancer activities. In the present investigation, the effect of different solvents, including methanol, acetone, and water on the total phenolic, flavonoid, antioxidant and antibacterial activities of Oscillatoria agardhii and Anabaena sphaerica extracts were evaluated. The results showed that solvents with different polarities have various effects on phenolic content and antioxidant activity. Among the tested solvents, methanolic extract of Oscillatoria agardhii showed the highest antioxidant activity as well as the highest phenolic content. Organic extracts (with methanol or acetone) of the tested species actively inhibited the growth of bacteria compared to aqueous extracts. The highest antibacterial activity was detected by acetone extract of Oscillatoria agardhii against Salmonella senftenberg. By GC-MS analysis some important heterocyclic compound were identified in both Oscillatoria agardhii and Anabaena sphaerica crude extracts. This appeared to be responsible for such excellent antioxidant and antibacterial activity together with other unidentified compounds. Further exploration of antibacterial potential of cyanobacteria can open new horizons.
Azza M. Abd El-Aty, Amal Amin Mohamed, Farag Samhan. In Vitro Antioxidant and Antibacterial Activities of Two Fresh Water Cyanobacterial Species, Oscillatoria agardhii and Anabaena sphaerica. J App Pharm Sci, 2014; 4 (07): 069-075.
401 Absract views 9 PDF Downloads 410 Total views
Synthesis and Antimicrobial studies of novel Benzimidazole derivatives
Characterization, in vitro cytotoxic and antibacterial exploitation of green synthesized freshwater cyanobacterial silver nanoparticlesGuna Swetha Kuraganti, Sujatha Edla, Thrimothy Dasari, Mamatha Reddy
In-Vitro Antioxidant potentials in leaves of Coleus aromaticus Benth and rhizomes of Zingiber zerumbet (L.) SM.Om Prakash Rout, Rabinarayan Acharya, Sagar Kumar Mishra
Determination of antioxidant and antimutagenic activities of Phlomis armeniaca and Mentha pulegium