Review Article | Volume: 4, Issue: 2, February, 2014

Orally Disintegrating Tablets: An Overview

Evren ALÄžIN YAPAR   

Open Access   

Published:  Feb 27, 2014

DOI: 10.7324/JAPS.2014.40219
Abstract

Orally disintegrating tablets (ODTs) have greatly increased dosage forms which have remarkable impact on the patient compliance especially for the pediatric, geriatric and psychiatric patients with deglutition disorders. Several technologies either conventional or patented based on freeze drying/lyophilization, spray drying, moulding, phase transition process, melt granulation, sublimation, mass extrusion, cotton candy process, direct compression etc. have been developed for manufacturing of ODTs. In this review brief information about ODTs including definition, ideal and desired characteristics, advantages, limitations and disadvantages, drug canditates, challenges in formulation, excipients with recent developments in superdisintegrants, tast masking, manufacturing techniques, evaluation parameters and recent patents in ODTs are presentented.


Keyword:     Deglutition disorders orally disintegrating tablets excipients taste masking patents.


Citation:

Evren ALÄžIN YAPAR. Orally Disintegrating Tablets: An Overview. J App Pharm Sci, 2014; 4 (02): 118-125.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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