Short Communication | Volume: 3, Issue: 12, December, 2013

Effect of Administration with Bacharris Dracunculifolia on Glycemic Basal Levels in Healthy Individuals

Tauana Aparecida de Oliveira,  Luiz Augusto da Silva,  Renan Garcia Michel,  André Luiz Snak,  Ricardo Aparecido Pereira,  Carlos Ricardo Maneck Malfatti,  Sirval de Oliveira Neto,  Andrieli Pereira Woellner,  Andressa Razera Pezoti,  Letícia Magri Dallastra,  Guilherme Augusto Gomes Martins   
Tauana Aparecida de Oliveira1, Luiz Augusto da Silva1, Renan Garcia Michel2, André Luiz Snak2, Ricardo Aparecido Pereira2, Carlos Ricardo Maneck Malfatti3, Sirval de Oliveira Neto4, Andrieli Pereira Woellner4, Andressa Razera Pezoti4, Letícia Magri Dallastra4, Guilherme Augusto Gomes Martins4

1Department of Physical Education, Midwest State University of Parana, Irati, PR, Brazil.

2Department of Biomedicine, Campo Real College, Guarapuava, PR, Brazil.

3Department of Physiotherapy, Midwest State University of Parana, Guarapuava, PR, Brazil.

4Department of Pharmacy, Midwest State University of Parana, Guarapuava, PR, Brazil.

Open Access   

Published:  Dec 30, 2013

DOI: 10.7324/JAPS.2013.31227
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Abstract

Some compounds found in B. dracunculifolia could be part of human diets, directly and indirectly through green propolis intake, because of their possible effect on blood glucose that could be of great relevance in the control of hyperglycemia; however, this effect has not been extensively studied. This study analyzed the effect of acute administration of B. dracunculifolia extracts on glycemic response in healthy individuals during rest. The study group consisted of eight healthy individuals at the age of 19 ± 1.3 years old, four in the treatment group (TG) and four in the control group (CG), with and without intake of 20 g/Kg of body weight of B. dracunculifolia extract, respectively. The cardiovascular parameters of blood pressure (BP) and heart rate (HR), and blood glucose (BG) were analyzed before and after treatments Statistical significance was determined using an unpaired Student's t-test and considering p<0.05. The TG group showed increase of 3% in heart rate (2 beats min-1, P<0.05), 11% in DBP scores, and reduction of 27% (20 mg/dl, P<0.05) in BG levels. The intake of B. dracunculifolia extract may help control blood glucose levels; however, its effects on the cardiovascular system must be evaluated in further studies.


Keyword:     Baccharis dracunculifolia Blood glucose Therapeutic agent antidiabetic.

Citation:

Tauana Aparecida de Oliveira, Luiz Augusto da Silva, Renan Garcia Michel, André Luiz Snak, Ricardo Aparecido Pereira, Carlos Ricardo Maneck Malfatti, Sirval de Oliveira Neto, Andrieli Pereira Woellner, Andressa Razera Pezoti, Letícia Magri Dallastra, Guilherme Augusto Gomes Martins. Effect of Administration with Bacharris Dracunculifolia on Glycemic Basal Levels in Healthy Individuals. J App Pharm Sci, 2013; 3 (12): 148-151.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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