Research Article | Volume: 3, Issue: 12, December, 2013

Antibacterial efficacy of Pimenta dioica (Linn.) Merill and Anacardium occidentale L. against drug resistant urinary tract pathogens

Manasa M Yashoda Kambar Sachidananda Swamy H.C. Vivek M.N Ravi Kumar T.N. Prashith Kekuda T.R   

Open Access   

Published:  Dec 30, 2013

DOI: 10.7324/JAPS.2013.31213
Abstract

The aim of the present study was to determine antibacterial effect of leaf and bark extracts of Pimenta dioica (Linn.) Merill (Myrtaceae) and Anacardium occidentale L. (Anacardiaceae) against drug resistant clinical isolates of urinary tract infection viz., Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus and Enterococcus faecalis. Agar well diffusion method was employed to assess inhibitory activity of leaf and bark extracts. Among extracts, bark extract of P. dioica and leaf extract of A. occidentale exhibited high inhibitory activity. The bark extract of P. dioica showed high inhibition of clinical isolates than other extracts. Among bacteria, E. faecalis and K. pneumoniae were inhibited to high and least extent respectively. The inhibitory potential of extracts could be attributed to the presence of bioactive secondary metabolites. Isolation of inhibitory principles from crude extracts and their inhibitory activity against UTI pathogens are to be carried out.


Keyword:     Pimenta dioica Anacardium occidentale Urinary tract infection Agar well diffusion.


Citation:

Manasa M, Yashoda Kambar, Sachidananda Swamy H.C, Vivek M.N, Ravi Kumar T.N, Prashith Kekuda T.R. Antibacterial efficacy of Pimenta dioica (Linn.) Merill and Anacardium occidentale L. against drug resistant urinary tract pathogens. J App Pharm Sci, 2013; 3 (12): 072-074.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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