Research Article | Volume: 3, Issue: 10, October, 2013

Hyptis brevipes (Lamiaceae) Extracts Strongly Inhibit the Growth and Development of Spodoptera littoralis (Boisd.) Larvae (Lepidoptera: Noctuidae)

Hanem H. Sakr Shimaa H. Roshdy and Hesham R. El-Seedi   

Open Access   

Published:  Oct 31, 2013

DOI: 10.7324/JAPS.2013.31014
Abstract

Hyptis brevipes (Lamiaceae) extracts are shown to exhibit strong insecticidal activity against the 3rd instar larva of the cotton leaf worm Spodoptera littoralis (Boisd.) (Lepidoptera: Noctuidae), inducing complete larval mortality due to the arrest and/or disruption of metamorphosis. This disruption induced a wide range of abnormalities. The LC50 value of the dichloromethane extract of H. brevipes was 3.0% (95% F.L. = 2.2% - 4.4%; slope = 3.185± 0.952) after three days of treatment. Two active compounds were isolated from the extract following bioassay-guided fractionation and were identified as 5-hydroxy-7,4'-dimethoxy-flavon-3-ol and 5-hydroxy-7-methoxy-2-(4`-methoxy-phenyl)-chromen-4-one based on spectroscopic data. This is the first report of these secondary metabolites in H. brevipes.


Keyword:     Hyptis brevipes Lamiaceae Spodoptera littoralis growth disruption flavonoids.


Citation:

Hanem H. Sakr, Shimaa H. Roshdy and Hesham R. El-Seedi. Hyptis brevipes (Lamiaceae) Extracts Strongly Inhibit the Growth and Development of Spodoptera littoralis (Boisd.) Larvae (Lepidoptera: Noctuidae). J App Pharm Sci, 2013; 3 (10): 083-088.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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