Research Article | Volume: 3, Issue: 10, October, 2013
Research Article | Volume: 3, Issue: 10, October, 2013
The main objective of the prospective study is to investigate the influence of zyloric (allopurinol) drug on the human hormones profile. Sera separated from whole blood samples were withdrawn from adult males and females to measure serum FSH, E2, LH, Prolactin, Progesterone, DHEAS, Testosterone, TSH, T3, T4, Fasting Insulin, and Cortisol. All these hormone concentrations were determined quantitatively using ELISA procedure. The current study shows significant changes within all volunteers' hormones. We concluded that the present study may be useful in drug dose optimization depending on the drug effect on each human hormone and in the addition of new medical guidelines for drug companies to avoid negative side effects that could harm the patient.
Emad F. Eskander, Ahmed A. Abd-Rabou, Hanaa H. Ahmed. Does Anti-Gout Agent Allopurinol Affect Human Hormones Profile? J App Pharm Sci, 2013; 3 (10): 079-082.
Year
Month
Effect of the fractions of Erythrina stricta leaf extract on serum urate levels and Xo/Xdh activities in oxonate-induced hyperuricaemic mice
Remya Raju, Sigimol Joseph, Soniya Scria, Santhosh M Mathews, M. UmamheshwariTreatment efficacy of febuxostat compared with allopurinol in hyperuricemia patients with hypertensive: A randomized, single-blind controlled trial
Son Kim Tran, Binh Thanh Huynh, Cuong Tan Vo, Truyen Van Ngo, Bao Lam Thai Tran, Khoa Dang Dang Tran, Phuong Minh Vo, Diem Thi Nguyen, Toan Hoang Ngo, An Viet Tran