Research Article | Volume: 3, Issue: 6, June, 2013

Prothrombin time and Activated Partial Thromboplastin time in Pregnant Women in Southern Nigeria

Avwioro OG Ezeobi JO Oduola T Fakunle OO   

Open Access   

Published:  Jun 27, 2013

DOI: 10.7324/JAPS.2013.3631

The incidence of bleeding during and after child birth has become an issue of concern in maternal health. Prothrombin time and activated partial thromboplastin time in antenatal women in the three trimesters were studied in Southern Nigeria. 120 subjects were recruited for the study, consisting of 30 pregnant women each at first, second and third trimesters and 30 non pregnant women as the control. The tests were carried out using standard techniques. The result of the PT showed no statistically significant (P>0.05) difference in the first and third trimesters except in the second trimester (P<0.05). Activated partial thromboplastin time increased significantly in all the trimesters when compared with the control group. A decrease in coagulation factors of the intrinsic pathway could be responsible for the prolonged APTT in all the trimesters.

Keyword:     Prothrombin time activated partial thromboplastin t


Avwioro OG, Ezeobi JO, Oduola T, Fakunle OO., Prothrombin time and Activated Partial Thromboplastin time in Pregnant Women in Southern Nigeria. J App Pharm Sci. 2013; 3 (06): 179- 181.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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