Research Article | Volume: 3, Issue: 5, May, 2013

Antibacterial and Phytochemical studies of three Acanthaceae species used in Burkina Faso traditional medicine

Ouattara Nabèrè Hilou Adama Guenné Samson Konaté Kiessoum Zerbo Patrice Meda Nâg-Tiero Roland Compaoré Moussa Kiendrébeogo Martin Millogo F. Jeanne and Nacoulma O. Germaine   

Open Access   

Published:  May 30, 2013

DOI: 10.7324/JAPS.2013.3510

New and innovative antibacterial drugs research from plants is a best strategy to overcome the world problem about bacterial diseases. The aim of this study was to evaluate the in-vitro antibacterial activity and the phytochemical profile of various extracts from Hygrophila auriculata (Schumach.) Heine, Nelsonia canescens (Lam) Spreng and Peristrophe bicalyculata (Retz.) Nees; three acanthaceae species widely used in folk medicine of Burkina Faso. The inhibition diameter determination of the eleven bacteria strains and the Minimum Inhibition Concentration (MIC) of the plants extracts and fractions were evaluated using standards methods. All extracts were also evaluated for their phenolic contents. The results showed that all extracts and fractions exhibited good bacteria inhibition and have a wealth of phenolic compounds. Comparing the MIC of extracts and fractions, E. coli (CPI: 105182) strain was best inhibited and N. canescens butanol fraction presented the best activity. As regard phytochemical profile, highest values of total phenolics, total flavonoids, total flavonols and total tannins were obtained with N. canescens fractions. The results could justify the traditional used of these species against infectious diseases. This study shows that these three medicinal plants and especially N. canescens are good candidate for isolate new et innovative antibacterial compounds.

Keyword:     Hygrophila auriculata Nelsonia canescens


Ouattara Nabèrè, Hilou Adama, Guenné Samson, Konaté Kiessoum, Zerbo Patrice, Meda Nâg-Tiero Roland, Compaoré Moussa, Kiendrébeogo Martin, Millogo F. Jeanne and Nacoulma O. Germaine., Antibacterial and Phytochemical studies of three Acanthaceae species used in Burkina Faso traditional medicine. J App Pharm Sci, 2013; 3 (05): 049-055.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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