Research Article | Volume: 3, Issue: 4, Supplement: 1, May, 2013

Ameliorative Effects of Vitamin C and E on Serum Lipid Profiles and Liver Enzymes on Fructose induced hyperglycaemia in Wistar Rats

Tanko Y.Eze E. D.Daja H. S. Jimoh A.Mohammed K. A. and K.Y. Musa   

Open Access   

Published:  May 12, 2013

DOI: 10.7324/JAPS.2013.34.S15
Abstract

The aim of this study is to determine the effect of vitamin C and E administration on serum lipid profiles and liver enzymes on fructose-induced diabetes on Wistar rats. Diabetes was induced by administration of 20% (20g/100ml) of fructose dissolved in distilled water for a period of six (6) weeks to the animals. After which the animals were randomly assigned into 4 groups of 6 rats each. Group 1 (control) administered distilled water, Group 2 administered vitamin C (100mg/kg b w), Group 3 administered vitamin E (100mg/kg b w) and Group 4 administered Metformin (250 mg/kg b w). The results obtained showed a statistical significant reduction (p


Keyword:     Hyperglycemia Vitamin C Vitamin E Lipid profile


Citation:

Tanko Y., Eze E. D., Daja H. S., Jimoh A., Mohammed K. A. and K.Y.Musa., Ameliorative Effects of Vitamin C and E on Serum Lipid Profiles and Liver Enzymes on Fructose induced hyperglycaemia in Wistar Rats. J App Pharm Sci, 2013; 3 (4 Suppl 1), S80-S84.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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