Research Article | Volume: 3, Issue: 4, April, 2013
Research Article | Volume: 3, Issue: 4, April, 2013
A simple, selective, linear, precise and accurate RP-HPLC method was developed and validated for rapid assay of Gliclazide in pharmaceutical dosage form. Isocratic elution at a flow rate of 1.2 ml min -1 was employed on a symmetry C18 column at ambient temperature. The mobile phase consisted of methanol: phosphate buffer 50:50 (V/V). The UV detection wavelength was at 210 nm. Linearity was observed in concentration range of 1-100 µg/mL. The retention time for Gliclazide was 3.25 min. The method was validated as per the ICH guidelines. The proposed method can be successfully applied for the estimation of Gliclazide in pharmaceutical dosage forms.
B.V.V Ravi kumar, A.K. Patnaik, Saroj Kumar Raul, Nagireddy Neelakanta Rao, A RP-HPLC Method Development and Validation for the Estimation of Gliclazide in bulk and Pharmaceutical Dosage Forms. J App Pharm Sci, 2013; 3 (04): 059-062.
Year
Month
Pharmacological and Pharmaceutical Profile of Gliclazide: A Review
Ananya Sarkar, Ajay Tiwari, Parminder S. Bhasin, Moloy MitraDevelopment and Validation of RP-HPLC Method for the Simultaneous Estimation of Domperidone and Naproxen in Tablet Dosage Form
Md. Shozan Mondal, Md. Ahsanul Haque, Mohammad Safiqul Islam, S.M. Ashraful IslamUPLC method development and validation for Cefditoren Pivoxil in active pharmaceutical Ingredient
Ram Garg, Navneet Singh, Kona S. Srinivas, Binayak Deb, Ayaz AhmedA validated stability indicating HPLC method for the determination of Valsartan in tablet dosage forms