Research Article | Volume: 3, Issue: 3, March, 2013

Gas Chromatography-Mass Spectrometry (GC-MS) Analysis of Bioactive Components of Ethyl acetate Root Extract of Guiera senegalensis J.F. Gmel

Shettima AY Karumi Y Sodipo OA Usman H and Tijjani MA   

Open Access   

Published:  Mar 28, 2013

DOI: 10.7324/JAPS.2013.30328
Abstract

Guiera senegalensis J.F. Gmel is used in West African Ethnomedicine for treating diarrhoea, dysentery, malaria, cough and microbial infections. The methanol and ethyl acetate root extracts of G. senegalensis have been shown to be effective against diarrhoea and also have antibacterial activity. The plant was therefore investigated for its bioactive components. The ethyl acetate root extract was investigated using Gas Chromatography-Mass Spectrometry (GC-MS) analysis. Nine components were identified, n-Hexadecanoic acid (46.6%) as the major component followed by 9-Hexadecenoic acid (20.93%), methyl ester (7.75%), 7-Octadecenoic acid- methyl ester, 1, 2-benzene dicarboxylic acid – diisoctyl ester having (6.97%) respectively; 2–pentanone - 4–hydroxy–4–methyl acid diethyl phthalate (2.32%), Decane–6–ethyl–2–methyl and nonane, 3–7–dimethyl with (1.55%) compositions respectively.


Keyword:     G.senegalensis Ethyl acetate GC-MS and Bioactive components.


Citation:

Shettima AY, Karumi Y, Sodipo OA, Usman H and Tijjani MA., Gas Chromatography–Mass Spectrometry (GC-MS) Analysis of Bioactive Components of Ethyl acetate Root Extract of Guiera senegalensis J.F. Gmel. J App Pharm Sci. 2013; 3 (03): 146-150.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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