Research Article | Volume: 3, Issue: 3, March, 2013

Preliminary Phytochemical Studies and Evaluation of Antidiabetic Activity of Roots of Cayratia trifolia (L.) Domin in Alloxan Induced Diabetic Albino Rats

Shikha Batra Nikhil Batra and Badri Prakash Nagori   

Open Access   

Published:  Mar 28, 2013

DOI: 10.7324/JAPS.2013.30319
Abstract

The present study aims to investigate the antidiabetic activity of roots of Cayratia trifolia (L.) Domin in alloxan induced diabetic rats. Phytochemical studies showed the presence of steroids, flavonoids and alkaloids in petroleum ether, ethyl acetate and ethanol extracts, respectively. Antidiabetic activity was evaluated by observing blood glucose levels and analyzing the serum biochemical parameters after dosing the ethyl acetate extract. Blood samples were collected from overnight fasted diabetic rats on 5, 10 and 15 days of treatment to determine blood glucose levels. On day 16, blood samples were collected to estimate the biochemical parameters. In diabetic rats, both the doses (200 mg/kg and 400 mg/kg) of ethyl acetate extract were found to be significant (P


Keyword:     Antidiabetic Hypoglycemic Cayratia trifol


Citation:

Shikha Batra, Nikhil Batra, and Badri Prakash Nagori., Preliminary Phytochemical Studies and Evaluation of Antidiabetic Activity of Roots of Cayratia trifolia (L.) Domin in Alloxan Induced Diabetic Albino Rats. J App Pharm Sci. 2013; 3 (03): 097-100.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

HTML Full Text

Reference

Article Metrics
572 Views 13 Downloads 585 Total

Year

Month

Related Search

By author names