Research Article | Volume: 3, Issue: 3, March, 2013

Anticariogenic Activity of Gnidia glauca (Fresen.) Gilg, Pothos scandens L. and Elaegnus kologa Schlecht

Syed Junaid Dileep N Rakesh K.N Pavithra G.M Vinayaka K.S Prashith Kekuda T.R   

Open Access   

Published:  Mar 28, 2013

DOI: 10.7324/JAPS.2013.30304

The present study was conducted to estimate total phenolic and flavonoid content and to determine anticariogenic efficacy of methanol extract of Gnidia glauca (Fresen.) Gilg (Thymelaeaceae), Pothos scandens L. (Araceae) and Elaegnus kologa Schlecht (Elaeagnaceae) leaves. Total phenolic and flavonoid content of leaf extracts was determined by Folin-Ciocalteau method and Aluminium chloride colorimetric estimation method respectively. Anticariogenic activity of leaf extracts was assessed against 13 clinical isolates of Streptococcus mutans by Agar well diffusion technique. The contents of total phenolics and flavonoids were higher in G. glauca followed by P. scandens and E. kologa. The extract of G. glauca showed greater inhibition of cariogenic isolates than P. scandens and E. kologa as revealed by wider inhibition zones. The study revealed a correlation between the amount of phenolics and flavonoids present in the extracts and the anticariogenic activity of the extracts. The plants used in this study could be used against dental caries.

Keyword:     Gnidia glauca Pothos scandens Elaegnus kologa Total phenolic Flavonoid Dental caries.


Syed Junaid, Dileep N, Rakesh K.N, Pavithra G.M, Vinayaka K.S, Prashith Kekuda T.R., Anticariogenic Activity of Gnidia glauca (Fresen.) Gilg, Pothos scandens L. and Elaegnus kologa Schlecht. J App Pharm Sci. 2013; 3 (03): 020-023.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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