Research Article | Volume: 3, Issue: 1, January, 2013

Effect of Treatment With Msg on Growth, Satiety and Epididymal Adiposity in Neonatal Rats

Leandro Coelho Lemos José Augusto Pochapski Allan Raczenski Luiz Augusto da Silva Thiago Emannuel Medeiros Palloma Almeida Soares Hocayen Janaina Ângela Turmina Carlos Ricardo Maneck Malfatti   

Open Access   

Published:  Jan 28, 2013

DOI: 10.7324/JAPS.2013.30105

This study aims to evaluate the relationship between morphological and metabolic parameters in obese rats induced by MSG, using exercise to determine the glycemic response between animals. Were constituted by 10 adult female Wistar rats, 4-month-old boy with obesity induced by MSG. They measured levels of intake of food and water for a week, and after, there was a swimming test lasting 60 minutes. The results are expressed as mean and standard deviation. It was used the Student t-test for independent samples, a significant difference when considering p<0.05. Occur significant difference between the length of the small intestine, where the obese group has the gut lower 14% (13 cm) compared to the normal group (p<0.05). Regarding the body weight, the average weight of the MSG group was significantly lower (82%; 37g, p<0.05) compared to the Control group. The opposite occurred with visceral adiposity, performing significantly higher in MSG group (54%; 8g, p<0.05) from the average of the Control group. We conclude that the consumption of MSG may lead to obesity by increasing body fat and visceral also morphological differences in the size of the gut and body weight.

Keyword:     Obesity Intestine Glycemia Exercise.


Leandro Coelho Lemos; José Augusto Pochapski; Allan Raczenski; Luiz Augusto da Silva; Thiago Emannuel Medeiros; Palloma Almeida Soares Hocayen; Janaina Ângela Turmina, Carlos Ricardo Maneck Malfatti., Effect of Treatment with Msg on Growth, Satiety and Epididymal Adiposity in Neonatal Rats. J App Pharm Sci. 2013; 3 (01): 021-025.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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