Neuromuscular blockers are used during surgery with anesthesia to cause relaxation of muscles and control muscle movements. The purpose of this review is to focus on the synthesis and pharmacological activity of the neuromuscular blockers, to compare the main differences between the available polarizing and non-depolarizing neuromuscular blockers. Continuous improvement of knowledge about neuromuscular blockers in respect to synthesis, their pharmacology, adverse effects, and toxic effects were unanswered questions about neuromuscular junction and neuromuscular blockade in children is essential for the correct use of these drugs. In this review article, structure-activity relationships within polarizing and non-depolarizing neuromuscular blockers have been reviewed.
Pranay Jain and Priyanka Sharm. Probiotics and Their Efficacy in Improving Oral Health: A Review J App Pharm Sci. 2012; 2 (11): 151-163.
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