Review Article | Volume: 2 Issue: 11, November, 2012

Azasteroids as Promising Neuromuscular Blockers: A Review

Prafulla M Sabale Prashant Prajapati Pratik G Kalal Drishti B Nagar   

Open Access    DOI: 10.7324/JAPS.2012.21129


Neuromuscular blockers are used during surgery with anesthesia to cause relaxation of muscles and control muscle movements. The purpose of this review is to focus on the synthesis and pharmacological activity of the neuromuscular blockers, to compare the main differences between the available polarizing and non-depolarizing neuromuscular blockers. Continuous improvement of knowledge about neuromuscular blockers in respect to synthesis, their pharmacology, adverse effects, and toxic effects were unanswered questions about neuromuscular junction and neuromuscular blockade in children is essential for the correct use of these drugs. In this review article, structure-activity relationships within polarizing and non-depolarizing neuromuscular blockers have been reviewed.

Keyword:     Neuromuscular blockers Quaternary ammonium muscle relaxants depolarizing neuromuscular blockers Non-depolarizing Neuromuscular blockers Bisquaternary azasteroids.


Pranay Jain and Priyanka Sharm. Probiotics and Their Efficacy in Improving Oral Health: A Review J App Pharm Sci. 2012; 2 (11): 151-163.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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