Research Article | Volume: 2 Issue: 10, October, 2012

Polysaccharides of the red algae 'Pterocladia' growing on the Lebanese coast: Isolation, structural features with antioxidant and anticoagulant activities

C. Sebaaly N. Karaki N. Chahine A. Evidente A. yassine J. Habib and H. Kanaan   

Open Access    DOI: 10.7324/JAPS.2012.21001

Abstract

In addition to their high nutritional value, red algae are of great interest as a source of therapeutic substances. However, despite their abundance on the Lebanese coast red algae have never been studied before. Therefore, we attempted to study among the available biomass one of the species of red algae growing on the Lebanese coast “Pterocladia”. We performed the extraction of trace elements, fatty acids, sulfated galactans and water-soluble polysaccharides of the phycocolloids family (carrageenans) whose physicochemical gelling or stabilizing effects attract many industrial sectors. The analysis of trace elements shows large amounts of potassium, calcium, silicon and iron. Moreover, Pterocladia appears to be rich in saturated fatty acids (69%) with palmitic acid as major fatty acid and 31% of monounsaturated fatty acids. The extraction yields were 2.7% for sulfated galactans and 11.5% for carrageenan. In order to elucidate their structures, H¹ NMR spectroscopy was performed as well as Infra-Red spectroscopy which allowed us to reveal their functional groups. A study of the antioxidant effect by the electrolysis method showed a greater effect for sulfated galactans. Furthermore, the study of the anticoagulant effect by APTT test, activated partial thromboplastin time, showed more pronounced anticoagulant power of sulfated galactans. The results of the present study confirmed the potential use of the red algae Pterocladia as a source of active known molecules.


Keyword:     Antioxidantanticoagulant activitiescarrageenansNMR and Infra-Red Spectroscopyred algaesulfated galactans.


Citation:

C. Sebaaly, N. Karaki, N. Chahine A. Evidente A. yassine, J. Habib and H. Kanaan. Polysaccharides of the red algae “Pterocladia” growing on the Lebanese coast: Isolation, structural features with antioxidant and anticoagulant activities . J App Pharm Sci. 2012; 2 (10): 001-010.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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