Research Article | Volume: 2 Issue: 8, August 2012
Open Access DOI: 10.7324/JAPS.2012.2838
DNA profiling of two closely related ornamental plants belonging to family crassulaceae viz. Kalanchoe thrysiflora Harv. and Kalanchoe marmorata Baker were performed to establish genetic polymorphism. Biological guided fractionation of the two plant extracts to assess their cytotoxicity, had led to the isolation of one steroidal and one triterpenoidal compound from the most active dichloromethane fraction of Kalanchoe thrysiflora. The cytotoxicity of the isolated compounds were evaluated against normal (HFB4) and cancer (MCF7) cells. Compound 1 (3-oxo-olean-12-ene) and compound 2 (β-sitosterol) showed similar cytotoxic activity on MCF7 at IC50 17.4 and 17.6 µg/ml respectively while on HFB4, the compounds revealed cytotoxic activity at IC50 21.9 and 21.6 respectively.
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Assessment of cytotoxicity, antibacterial activity and phytochemical screening of ethanol extract of Phyllanthus acidus L. (family: Euphorbiacceae) Bark
Subrata Kumar Biswas, Anusua Chowdhury, Joysree Das, Utpal Kumar Karmakar, Manik Chandra Shill, Sheikh Zahir RaihanGenetic Profiling, Chemical Characterization and Biological Evaluation of Two Conyza Species Growing in Egypt