Research Article | Volume: 2 Issue: 9, September, 2012
Isolation of a novel triterpene from the Essential oil of fresh leaves of Chromolaena odorata and its in-vitro cytotoxic activity against HepG2 cancer cell line
Open Access DOI: 10.7324/JAPS.2012.2926
The essential oil from the fresh leaves of Chromolaena odorata (Asteraceae) (L.) R.M. King & H. Rob. was obtained by hydro distillation. From the essential oil the compound (I) a triterpene derivative was isolated by column chromatography and it was characterized by IR, 1H-NMR, 13C-NMR and MS spectral data. It was screened for cytotoxicity against HepG2 by MTT assay. It showed significant cytotoxicity with IC50 value of 206.7 μg/ml towards HepG2 cancer cell line.
Velliangiri Prabhu and Subban Ravi. Isolation of a novel triterpene from the Essential oil of fresh leaves of Chromolaena odorata and its in-vitro cytotoxic activity against HepG2 cancer cell line J App Pharm Sci. 2012; 2(9): 132-136.