Research Article | Volume: 2 Issue: 9, September, 2012

Isolation of a novel triterpene from the Essential oil of fresh leaves of Chromolaena odorata and its in-vitro cytotoxic activity against HepG2 cancer cell line

Velliangiri Prabhu and Subban Ravi   

Open Access    DOI: 10.7324/JAPS.2012.2926

Abstract

The essential oil from the fresh leaves of Chromolaena odorata (Asteraceae) (L.) R.M. King & H. Rob. was obtained by hydro distillation. From the essential oil the compound (I) a triterpene derivative was isolated by column chromatography and it was characterized by IR, 1H-NMR, 13C-NMR and MS spectral data. It was screened for cytotoxicity against HepG2 by MTT assay. It showed significant cytotoxicity with IC50 value of 206.7 μg/ml towards HepG2 cancer cell line.


Keyword:     Chromolaena odorata IR 1H-NMR 13C-NMRMS spectra triterpene Cytotoxicity.


Citation:

Velliangiri Prabhu and Subban Ravi. Isolation of a novel triterpene from the Essential oil of fresh leaves of Chromolaena odorata and its in-vitro cytotoxic activity against HepG2 cancer cell line J App Pharm Sci. 2012; 2(9): 132-136.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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