Open Access DOI: 10.7324/JAPS.2012.2902
Marine invertebrate -associated bacteria are one of potential and prolific sources to produce unique and novel structure of bioactive compounds. Unsuitable growth media for cultivation of bacteria result in many bioactive compounds were not produced. Moraxella sp. RA15 was successfully isolated from Acropora dibranchiata. In an attempt to introduce bioactive compounds of Moraxella sp. RA15 was evaluated through various media and bioassays to find out the antimicrobial, antiplasmodial, and herbicidal potency as well as toxicity property. The Moraxella sp. RA15 extract in 1/10ZoBell agar medium showed herbicidal activity, toxicity against brine shrimp and antimicrobial activity against Bacillus subtilis, Pseudomonas aeruginosa, and Staphylococcus aureus. The antiplasmodial activity was only showed by Moraxella sp. RA15 extract produced in 1/10ZoBell broth medium. It can be concluded that medium and culture condition are important factors in bioactive compound production from bacteria.
Risa Nofiani, Rizmahardian Ashari Kurniawan, Tika Mabella, Puji Ardiningsih, Titin Anita Zahara and Sunarto. Study of Media Effect toward Antimicrobial, Antiplasmodial, Herbicidal Activities and Toxicity of Extract Produced by AcroporadibranchiataAssociated Moraxellasp. RA15. J App Pharm Sci. 2012; 2(9): 010- 014.
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