Review Article | Volume: 2 Issue: 7, July 2012
In-vivo and in-vitro screening of medicinal plants for their anti-inflammatory activity: an overview
Open Access DOI: 10.7324/JAPS.2012.2704
Review Article | Volume: 2 Issue: 7, July 2012
Open Access DOI: 10.7324/JAPS.2012.2704
Despite the progress made in medical research for the past decades, the treatment of many serious diseases is still problematic. Inflammation is the response of living tissues to injury. It involves a complex array of enzyme activation, mediator release, extravasations of fluid, cell migration, tissue breakdown and repair. Inflammation has become the focus of global scientific research because of its implication in virtually all human and animal diseases. As a result of adverse effects such as gastric lesions caused by non-steroidal anti-inflammatory drugs (NSAID), tolerance and dependence induced by opiates, the use of these drugs as anti-inflammatory agents have not been successful in all cases. Therefore, new anti-inflammatory drugs lacking these side effects are being researched as alternatives to NSAID and opiates. Attention is being focused on the investigation of the efficacy of plant-based drugs used in the traditional medicine because they are cheap, have little side effects. Hence, in the present review the various animal models used for preclinical screening anti-inflammatory activity herbs was compiled.
Year
Month
Topical anti-inflammatory action of Caryocar villosum oil (Aubl)Pers.
William Kalhy, Silva Xavier, Benedito Junior Medeiros, Clarissa Silva Lima, Hugo Alexandre Favacho, Eloisa Helena de Aguiar Andrade, Railda Neyva, Moreira Araujo, Lourivaldo Silva SantosVascular changes and acute inflammation induced by agar in the air pouch model
Synergistic effect of menthol on in-vitro antibacterial activity of Garcinia kola against Gram positive Bacteria: A preliminary study
Olumide Adedokun Odeyemi, Solakunmi O. Oluwajoba