Research Article | Volume : 2 Issue : 5, May 2012

Antioxidant and neuroprotective activities of essential oil, isolated from Chinese herb pairs of Angelica sinensis and Sophora flavescens

Aiyun Li,  Linna Han,  Chun Chao Han   
Aiyun Li1, Linna Han2, Chun Chao Han2

1Department of Pharmacy, The 2thAffiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan 250014, P.R China.

2School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, P.R China.

Open Access    DOI: 10.7324/JAPS.2012.2505

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Abstract

The antioxidant and neuroprotective activities of essential oil (EO), isolated from Chinese herb pairs of Angelica sinensis and Sophora flavescens were studied in this paper. EO significantly improved the outcome in rats after cerebral ischemia and reperfusion in terms of neurobehavioral function. EO treatment decreased the levels of tumor necrosis factor alpha, interleukin 1 beta and oxidative stress. Our results had showed that EO was a potent neuroprotective medicine.


Keyword:     Angelica sinensis Sophora flavescens Chinese herb pairs essential oil.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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