Research Article | Volume : 1 Issue : 3, May 2011

Quantitative determination of lamotrigi1ne in bulk and dosage form by UV Spectrophotometry

Navdeep Saini,  Koyal Saini   
Navdeep Saini1, Koyal Saini2

1Department of Quality Assurance, Mandsaur Institute of Pharmacy, Near MIT Campus, Rewas- Devda Road, Mandsaur, India.

2Department of Regulatory Affairs, Mandsaur Institute of Pharmacy, Near MIT Campus, Rewas- Devda Road, Mandsaur, India.

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Abstract

A new simple, rapid and precise spectroscopic method in UV region was developed for the quantitative determination of lamotrigine in bulk and in dosage form. In 0.1 M NaOH,Lamotrigine shows maximum absorbance at 307 nm. In proposed method Lamotrigine follows linearity in the concentration range 5-50 mcg/ml.The correlation coefficient for lamotrigine was found to be 0.99. The method was validated for Linearity, Precision and Accuracy.


Keyword:     Lamotrigine UV Spectroscopic Method.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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