Case Report | Volume: 8, Issue: 3, March, 2018

Diabetes Mellitus and Metformin: Fatal Vitamin B12 Deficiency Associated with Anemia and Sepsis in a Young Adult

Anuvarsha Katroth Anusha Narayanam Sheetal Chauhan Ajit Singh   

Open Access   

Published:  Mar 30, 2018

DOI: 10.7324/JAPS.2018.8322
Abstract

Metformin is recommended as the first-line therapy to treat type 2 diabetes mellitus with better efficacy. We present a young adult with severe fatigue and dyspnea along with difficulty during the walk and tingling sensation in both the lower limbs. He had T2DM for 9 years and continuing metformin 1 g daily for five years. He presented to the hospital with untreated wounds over lower limbs. His haematological reports showed the megaloblastic anemia and transfused with several pints of packed red blood cells (PRBCs). The patient developed sepsis during hospitalization and started on antibiotics. After several PRBC transfusions and aggressive treatment also patient did not improve and succumbed on 5th day of hospitalization.


Keyword:     Megaloblastic anemia Met¬formin-induced neuropathy Diabetic foot Diabetic ulcers.


Citation:

Katroth A, Narayanam A, Chauhan S, Singh A. Diabetes Mellitus and Metformin: Fatal Vitamin B12 Deficiency Associated with Anemia and Sepsis in a Young Adult. J App Pharm Sci, 2018; 8(03): 165-167.

Copyright: © The Author(s). This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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