Research Article | Volume: 8, Issue: 1, January, 2018

In vitro evaluation of photoprotective potential of the different solvent extracts of Graptophyllum pictum leaves

Khor Poh-Yen Seow Lay-Jing Fatin Hanani   

Open Access   

Published:  Jan 28, 2018

DOI: 10.7324/JAPS.2018.8122

Natural substances extracted from plants have been gaining attraction as protective agents due to their safety and responsible for multiple biological effects on skins. The present work evaluates the photoprotective potential of different solvent extracts of Graptophyllum pictum (G pictum) leaves, and the comparison of its Sun Protection Factor (SPF) value against photo-stability and thermal-stability under a 21-day of storage process. Preliminary phytochemical screening was also performed. The dried powdered leaves were extracted by cold maceration method, using five different solvent, i.e. methanol, ethanol, chloroform, ethyl acetate and hexane. The SPF of all extracts were analyzed by ultraviolet (UV) spectrophometry. The SPF results of the five types of extracts were found to have significant differences (P < 0.001). Methanol extract displayed the highest SPF value (15.303±0.045), while the lowest SPF value was showed by ethyl acetate extract. SPF reductions of all extracts under sun exposure condition were higher compared to the extracts placed in dark conditions at room temperature. As compared, the ethanol extract displayed better chemical and thermo-stability with higher in vitro SPF at 200 μg/ml. These findings suggested that ethanol was the solvent of choice for yielding high levels of photoprotective ingredients from G. pictum which can be used to formulate effective sunscreen preparations.

Keyword:     Solanum sisymbriifolium Solanaceae antinociceptive medicinal plant pain.


Poh-Yen K, Lay-Jing S, Hanani F. In vitro evaluation of photo protective potential of the different solvent extracts of Graptophyllum pictum leaves. J App Pharm Sci, 2018; 8 (01): 147- 151.

Copyright: © The Author(s). This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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