Research Article | Volume : 1 Issue : 8, October 2011

Structure determination of betulinic acid from the leaves of Lophira lanceolata Van Tiegh. Ex Keay (Ochnaceae)

Sani Audu Ali,  Rafat Ojuolape Abdulraheem,  Sikirat Sani Abdulkareem,  Emmanuel Taiwo Alemika,  Mohammed Ilyas   
Sani Audu Ali1, Rafat Ojuolape Abdulraheem2, Sikirat Sani Abdulkareem3, Emmanuel Taiwo Alemika4, Mohammed Ilyas5

1Department of Pharmaceutical Chemistry, University of Maiduguri , Nigeria.

2Department of Food Science and Technology, University of Maiduguri , Nigeria.

3Department of Chemistry, Federal Polytechnic, Damaturu, Yobe State, Nigeria.

4Department of Pharmaceutical and Medicinal Chemistry, University of Jos , Jos, Nigeria.

5Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria.

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Abstract

Cupressuflavone a biflavone was ealier isolated from the leaves of Lophira lanceolata. From this work Betulinic acid was also isolate from the leaves for the first time. The two compounds were identified on the basis of 1D NMR (1H, 13C and DEPT), 2D NMR (COSY, HSQC, HMBC and NOESY), IR, MS data and by comparison with reported data. Like that of Ouretia this recent isolation suggest that betulinic acid can be used as chemical markers in the Ochnaceae family.


Keyword:     betulinic acid Lophira lanceolata Ochnaceae Ex Keay.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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