Research Article | Volume: 7, Issue: 10, October, 2017

Comparison of Ionic Liquid-Microwave-Assisted Extraction and MAE of Resveratrol from Melinjo (Gnetum gnemon L.) Seeds

Maesya Rachmawati Imalia Nurrachma Ayuningtyas S. Sutriyo Abdul Mun’im   

Open Access   

Published:  Oct 30, 2017

DOI: 10.7324/JAPS.2017.71004

Purpose: This study investigated the effect of [Bmim]Br microwave assisted extraction (MAE), and MAE methods using ethanol on trans-resveratrol extraction from Melinjo (Gnetum gnemon) seeds.

Methods: The three-level response surface methodology was used to optimize extraction conditions for trans-resveratrol content from Melinjo seeds using MAE method and IL-MAE. Resveratrol content was determined using HPLC, and antioxidant activity was examined by DPPH assay.

Results: Compared to the MAE-ethanol method, then the optimum result of IL-MAE was reached with [Bmim] Br concentration 2.5 mol/L; microwave power

10%; and extraction time 10 min with the trans-resveratrol value 0.52 mg/g. The antioxidant activity value of IL-MAE melinjo seed extract was in 82.82% of DPPH inhibition.

Conclusion: This IL-MAE method was suitable to apply as an alternative technique to extract the active compound from the plant.

Keyword:     Microwave assisted extraction melinjo trans-resveratrolGnetum gnemon ionic liquid.


Rachmawati M, Ayuningtyas IN, Sutriyo S, Mun’im A. Comparison of Ionic Liquid-Microwave-Assisted Extraction and MAE of Resveratrol from Melinjo (Gnetum gnemonL.) Seeds. J App Pharm Sci, 2017; 7 (10): 023-029.

Copyright: © The Author(s). This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

HTML Full Text


Article Metrics

430 Absract views 16 PDF Downloads 446 Total views

   Abstract      Pdf Download

Related Search

By author names

Citiaion Alert By Google Scholar

Name Required
Email Required Invalid Email Address

Comment required