Research Article | Volume: 7, Issue: 7, July, 2017

The risk of cardiovascular events in persons with a non-cardiac pathology

Olga Khlynovaa Alexander Tueva Liubov Vasiletsa Ekaterina Shishkinab Sergey Naumovb Grigoriy Spasenkovb Tatiana Kalashnikovaa   

Open Access   

Published:  Jul 30, 2017

DOI: 10.7324/JAPS.2017.70730

Nowadays, one of the main areas in internal disease treatment is preventive medicine, which includes the risk measurement method. This method is often used in cardiology to assess both the chances of a disease’s emergence and its progression or complicated course. The purpose of this study was to investigate the possibilities of identifying factors of cardiovascular risks in people with gastroesophageal reflux disease and obesity. Eighty patients, whose average age was 47.1±5.5, were examined. The results of the study allowed distinguishing prognostic factors of cardiovascular risks for persons with isolated forms of gastroesophageal reflux disease and obesity, as well as their comorbidity. The developed formulas and models allow assessing the risk of cardiovascular diseases individually for obesity, gastroesophageal reflux disease, and the combination thereof. We determined the risk of cardiovascular diseases in obese people and gastroesophageal reflux disease patients, which results from the features of the chronobiologic indicators of the organism, the metabolic profile, and the degree of deleterious lesions of the esophageal mucosa in patients. The presented model characterizes the probability of emergence of cardiovascular diseases in patients with non-cardiac pathologies. This study can be used to design new methods for preventing cardiovascular events.

Keyword:     Cardiovascular disease model chronobiologic indicators discriminant analysis method gastroesophageal reflux disease obesity.


Khlynova O, Tuev A, Vasilets L, Shishkina E, Naumov S, Spasenkov G, Kalashnikova T. The risk of cardiovascular events in persons with a non-cardiac pathology. J App Pharm Sci, 2017; 7 (07): 208-211.

Copyright: © The Author(s). This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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