Research Article | Volume: 7, Issue: 6, June, 2017

Evaluation of antilipolytic, antioxidant and antibacterial activities of selected ferns

Rini Jarial Lakhveer Singh Sveta Thakur A. W. Zularisam Mimi Sakinah S. S. Kanwar   

Open Access   

Published:  Jun 30, 2017

DOI: 10.7324/JAPS.2017.70621
Abstract

In the present study, three ferns were used (Adiantum capillus-veneris Cheilanthes albomarginata and Asplenium pumilum) to identify their functional compounds to reduce obesity. The methanolic fern-extract (MFE) of these ferns was assessed for anti-bacterial activity by measuring inhibition zones against a panel of pathogenic bacterial strains using the agar diffusion method. MFE at a concentration of 25 μg /ml showed marked anti-bacterial activity against all bacterial strains (6mm to 23mm) zone of inhibition and was greatest against Enterobacter sp (23 mm). Out of these, the MFE of the A. veneris fern extract had the best MIC values of 2.25 μg /ml against S. aureus and Enterobacter sp. respectively. It had an inhibitory concentration (69.9 %) for 2, 2-diphenylpicryl-1-picryl-hydrazyl (DPPH) scavenging activity. The MFE of the A. veriens also possessed good anti-lipolytic activity (76.5%) against a porcine pancreatic lipase (PPL) and cholesterol oxidase inhibition (89%). The hemolytic activity of A. veneris was found to be 27.6% at 6.25 µg/mL of MFE. This result showed that the MFE of A. veriens is not only a potent source of natural anti-oxidants and anti-bacterial activities but also possesses efficient cholesterol degradation and anti-lipolytic activities, which would be beneficial in body weight management.


Keyword:     Adiantum capillus-veneris Cheilanthes albomarginata Asplenium pumilum Anti-oxidant Anti-lipolytic Anti-hemolytic.


Citation:

Jarial R, Singh L, Thakur S, Sakinah M, Zularisam AW, Kanwar SS. Evaluation of anti- lipolytic, anti-oxidant and anti-bacterial activities of selected ferns. J App Pharm Sci, 2017; 7 (06): 150-156.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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