Research Article | Volume: 7, Issue: 6, June, 2017

In vitro cytotoxicity analysis of sulfated polysaccharides from green seaweed Codium tomentosum Stackhouse, 1797

Pagolu Navya Samantha Sekar Khora   

Open Access   

Published:  Jun 30, 2017

DOI: 10.7324/JAPS.2017.70605
Abstract

Algae polysaccharides are commonly used in alternative medicine. Toxicity study of the isolated polysaccharide was carried out prior to the exploration of its bioactivities. In the present study we examined the toxicity of sulfated polysaccharides isolated from marine green algae Codium tomentosum. In this in vitro study, normal mouse fibroblast cells (L929) cells were used and Cytotoxicity was screened using 3-(4, 5-d imethylthiazol-2-yl)-2, 5 diphenyltetrazolium bromide (MTT) reduction assay. This study showed that Polysaccharides from Codium tomentosum had no toxic effects, so these polysaccharides can be utilized for future studies.


Keyword:     Codium tomentosum Polysaccharides Toxicity L929 cells MTT assay.


Citation:

Navya P, Khora SS. In vitro cytotoxicity analysis of sulfated polysaccharides from green seaweed Codium tomentosum Stackhouse, 1797. J App Pharm Sci, 2017; 7 (06): 033-036.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

HTML Full Text

Reference

Article Metrics
531 Views 74 Downloads 605 Total

Year

Month

Related Search

By author names