Panax quinquefolius L. is one of the most widely consumed and cultivated herbal medicines around the world. China and Canada are the two major producing countries. However, research on the ecotype distinction of P. quinquefolius from Canada has never been reported, and the quality evaluation of P. quinquefolius between China and Canada using nuclear magnetic resonance (1H-NMR) is limited. Here, we investigated the 1H NMR key signals and ecological factors of P. quinquefolius samples, and the data were further analyzed by principal component analysis (PCA) and partial least squares discriminant analysis (PLS-DA). The key signals were identified as sugar and methyl, which distinguished all the samples into two different ecotypes. This is the first report of ecotype division for P. quinquefolium worldwide. The results showed quality variation of P. quinquefolium from different geographic areas, implying the ecological adaptation and biodiversity. Our findings also demonstrate the critical need for improving quality and quality standardization, appropriate ecological regionalization and promoting industrialized development of P. quinquefolium.
Gu C, Wang Z, Wu L, Huang L. Quality Assessment and Ecotype Distinction for Panax quinquefolius L. from China and Canada by 1H NMR and Chemometrics. J App Pharm Sci, 2017; 7 (05): 018- 023.
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