Research Article | Volume: 7, Issue: 3, March, 2017

Evaluation of prescription pattern of psycholeptic medications at hospital discharge for patients with cardiovascular diseases in national cardiovascular disease hospital of Bangladesh

Mir Muhammad Nasir Uddin,  Mohammad Shah Hafez Kabir,  Md. Mamun Al-Amin ,  Mynul Hasan,  Talha Bin Emran,  Mohammad Touhidul Islam,  Md Ashiqul Islam,  Shahriar Ahmed   
Mir Muhammad Nasir Uddin1, Mohammad Shah Hafez Kabir2, Md. Mamun Al-Amin3 & 4, Mynul Hasan3, Talha Bin Emran5, Mohammad Touhidul Islam6, Md Ashiqul Islam1, Shahriar Ahmed1

1Department of Pharmacy, University of Chittagong, Chittagong 4331, Bangladesh.

2Department of Pharmacy, International Islamic University Chittagong, Chittagong-4203, Bangladesh.

3Department of Pharmaceutical Sciences, North South University, Bashundhara, Dhaka 1229, Bangladesh.

4Queensland Brain Institute, University of Queensland, Australia.

5Laboratory of Vaccinology and Applied Immunology, Kanazawa University School of Pharmacy, Kakuma-machi, Kanazawa 920-1192, Japan.

6Department of Pharmaceutical Technology, University of Dhaka, Dhaka, Bangladesh.

Open Access   

Published:  Mar 30, 2017

DOI: 10.7324/JAPS.2017.70304
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Abstract

Background: The association of mental disorder with cardiac disease is not a coincidence rather a strong relationship exists in between those two.

Objective: We investigated the prescription pattern of psycholeptic drugs during the discharge of patients in a national cardiovascular hospital.

Methods: Data was collected from the National Institute of Cardiovascular Diseases (NICVD) at Dhaka in Bangladesh. In total, 1076 prescriptions were collected randomly from July 2012 to June 2013. Data were analyzed by using the software Statistical Package for Social Science (SPSS, version 22).

Results: Benzodiazepine was the highest (99.3%) prescribed psycholeptic class while Bromazepam (87.49%) the highest advised molecule. Psycholeptics were advised for 15 (38.77%), 10 (19.91%), 30 (15.72%) and 7 (13.39%) days. The patient group without psycholeptic medication (M=6.64 day) spent significantly (p<0.05) a longer duration in the hospital compared to the psycholeptic medication (Mean=5.06 day) group. Age is significantly (p<0.05) associated with the duration of staying in hospital and polymorbidity. Also, polymorbidity (p<0.05) is significantly associated with the polypharmacy. No significant (p<0.05) correlation has been found between age and polypharmacy. Duration of psycholeptics intake was not significantly (p<0.05) related to either age, or polymorbidity,or length hospital stay. Conclusion: This study revealed that bromazepam is the utmost prescribed drug of choice at NICVD, Bangladesh. Frequent prescription of bromazepam indicates that this kind of patients’ needs enough sleep to reduce their mental stress.


Keyword:     Psycholeptic benzodiazepine bromazepam polypharmacy.

Citation:

Nasir Uddin MM, Kabir MSH, Al-Amin MM, Hasan M, Emran TB, Islam MT, Islam MA, Ahmed S. Evaluation of prescription pattern of psycholeptic medications at hospital discharge for patients with cardiovascular diseases in national cardiovascular disease hospital of Bangladesh. J App Pharm Sci, 2017; 7 (03): 017-023.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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