Research Article | Volume: 6, Issue: 4, April, 2016

Impact of Hemodialysis on Serum Zinc and Copper Level in CKD Patients

Shehab Elzain Hamad Balla Amar Mohamed Ismail   

Open Access   

Published:  Apr 30, 2016

DOI: 10.7324/JAPS.2016.60423

The aim of this study was to assess the effect of HD on zinc and copper level among CKD patients. A cross-sectional study included 40 subjects (15 female and 25 male) from academic hospital aged (22-80 years old) were included, timed pre and post-hemodialysis samples were collected. Serum zinc, copper, urea and creatinine were measured by using atomic absorption spectroscopy 210-VGP® and Mindray Bs-200 respectively, and BMI was estimated. Paired t-test analyses showed significant decrease in mean copper, urea and creatinine with p-value (0.025, 0.000 and 0.000) respectively, while significant increase was observed in zinc level p-value 0.035. Person's correlation showed positive correlation between change in zinc level and reduction in urea, and no correlation noted between change in serum copper level and reduction in urea and creatinine. In conclusion HD decrease copper and increase zinc as both are antagonists, might play a vital role in pathogenesis of related disorders in CKD Patients.

Keyword:     Zinc copper CKD dialysis and hemodialysis.


Amar Mohamed Ismail, Shehab Elzain Balla. Impact of Hemodialysis on Serum Zinc and Copper Level In Ckd Patients. J App Pharm Sci, 2016; 6 (04): 165-168.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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