Research Article | Volume: 5, Issue: 11, November, 2015

Psychometric Properties of Knowledge, Attitude, and Practice on Pharmacogenovigilance in Drug Safety Questionnaire in Medicine and Pharmacy Students: based on Exploratory Factor Analysis

Adamu Yau,  Rohayah Husain,  Aniza Abd Aziz,  Mohd Khairi Bin Zahri Johari,  Ab Fatah Bin Rahman,  Ramadan Mohamed Elkalmi,  Ya‟u Jamilu,  Mainul Haque   
Adamu Yau1, Rohayah Husain1, Aniza Abd Aziz1, Mohd Khairi Bin Zahri Johari2, Ab Fatah Bin Rahman2, Ramadan Mohamed Elkalmi3, Ya‟u Jamilu4, Mainul Haque1

1Faculty of Medicine, Universiti Sultan Zainal Abidin, Kampus Kota, Jalan Sultan Mahmud, 20400 Kuala Terengganu, Malaysia.

2Faculty of Health Sciences, Universiti Sultan Zainal Abidin, Kampus Kota, Jalan Sultan Mahmud, 20400 Kuala Terengganu, Malaysia.

3Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Malaysia.

4Department of Pharmacology and Therapeutics & Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmaceutical Sciences, Ahmadu Bello University, Zaria, +234 Zaria, Nigeria.

Open Access   

Published:  Nov 27, 2015

DOI: 10.7324/JAPS.2015.501103
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Abstract

Integration of Pharmacogenomics and Pharmacovigilance in the curricula of future healthcare professionals is essential towards individualized medicine and drug safety. Researchers are lacking in Knowledge, attitude and practice regarding pharmacogenovigilance in drug safety among Malaysian future health professionals. This study is to develop and validate a reliable questionnaire for evaluation of knowledge, attitude and practice of future Doctors and Pharmacists concerning Pharmacogenovigilance in drug safety. A 49-item self-administered questionnaire was developed from the literature. The content was validated by a panel of relevant experts followed by face validity. A pilot study on 100 respondents was conducted for reliability, followed by a cross-sectional study involving 247 participants in factor analysis. The content validity index of the whole questionnaire was 0.8%. The overall Cronbach’s Alpha was 0.8, with P<0.001. 67.4% of the total variance was explained by 13 factors, and we can conclude that the questionnaire is a valid and reliable instrument.


Keyword:     Pharmacogenovigilance Questionnaire Factor analysis KAP.

Citation:

Yau A, Husain R, Aziz AA, Johari MKBZ, Rahman AFB, Elkalmi RM, Jamilu Y, Haque M. Psychometric Properties of Knowledge, Attitude, and Practice on Pharmacogenovigilance in Drug Safety Questionnaire in Medicine and Pharmacy Students: based on Exploratory Factor Analysis. J App Pharm Sci, 2015; 5 (11): 015- 022.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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