Research Article | Volume: 5, Issue: 9, September, 2015

Antioxidant enhancing ability of different solvents extractable components of Talinum triangulare in some selected Tissue homogenates of Albino Rats -In vitro

Olakunle Bamikole Afolabi,  Omotade Ibidun Oloyede,  Isreal Idowu Olayide,  Tajudeen Olabisi Obafemi,  Obabiolorunkosi Joseph Awe,  Blessing Ariyo Afolabi,  Amos Sunday Onikani   
Olakunle Bamikole Afolabi1, Omotade Ibidun Oloyede2, Isreal Idowu Olayide1, Tajudeen Olabisi Obafemi1, Obabiolorunkosi Joseph Awe1, Blessing Ariyo Afolabi3, Amos Sunday Onikani1

1College of Science, Department of Biochemistry, Afe-Babalola University. P.M.B 5454, Ado-Ekiti, Ekiti State, Nigeria.

2Faculty of Science, Department of Biochemistry, Ekiti State University. P.M.B 5363, Ado-Ekiti, Ekiti State, Nigeria.

3Department of Biochemistry, Bowen University, Iwo, Osun State. Nigeria.

Open Access   

Published:  Sep 27, 2015

DOI: 10.7324/JAPS.2015.50911
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Abstract

Antioxidant contents, mostly from plant source have been the major combating components against membranous peroxidation that causes degenerative diseases and among others in the living cells. In this work, we did look into how ethanol and aqueous extractable components of Talinum triangulare could effectively and synergistically enhance the activities of antioxidant enzymes i.e superoxide dismutase (SOD) catalase (CAT) and reduced glutathione (GSH) activities in the different tissues used in vitro. Different methods were employed in the assay and the results showed significant (p < 0.05) increase in ethanolic extract when the GSH enhancing competencies were considered in the organs when compare with that of aqueous and relatively with the control, also, the levels of catalase activities (CAT) observed showed significant (p < 0.05) difference as observed in the organs. Considering the superoxide dismutase (SOD) activities, aqueous extract showed significant (p < 0.05) increase in the liver and brain while significant (p < 0.05) increase was only observed in the ethanolic extract in the kidneys tissue. Indisputably, it could be claimed based on these facts that, Talinum triangulare could enhance the activities of these antioxidant enzymes assayed for and in turns could be helpful in the phytotherapeutic management of common diseases associated with the hypoactivity of the enzymes when involve in the diet.


Keyword:     Antioxidants Talinum triangulare Catalase Superoxide dismutase Reduced glutathione.

Citation:

Afolabi OB, Oloyede OI, Olayide II, Obafemi TO, Awe JO, Afolabi BA, Onikani SA. Antioxidant enhancing ability of different solvents extractable components of Talinum traingulare in some selected Tissue homogenates of Albino Rat-In vitro. J App Pharm Sci, 2015; 5 (09): 056-061.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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