Research Article | Volume: 5, Issue: 7, July, 2015

The Antipyretic Activity of Leaves Extract of Ceiba pentandra Better than Gossypium arboreum

Nyi Mekar Saptarini Dytha Andri Deswati   

Open Access   

Published:  Jul 27, 2015

DOI: 10.7324/JAPS.2015.50718
Abstract

Background: The Indonesian people were used the leaves of silk cotton tree (Gossypium arboreum L.) and cotton tree (Ceiba pentandra Gaertn.) as an antipyretic, empirically. There is no scientific evidences on the antipyretic activity of these plants. Objective: The aim of this study is to determine the better antipyretic activity of the leaves extract of G. arboreum and C. pentandra in Swiss mice as an animal model. Methods: The steps of the study consisted of extraction, phytochemical screening, and antipyretic activity assay on Swiss mice which induced by 20% yeast suspension. Results: The results showed that the leaves extract of G. arboreum and C. pentandra have antipyretic activity. The effective dose of antipyretic activity for the leaves extract of G. arboreum and C. pentandra is 1120 mg/kg and 189 mg/kg, respectively. Conclusion: The antipyretic activity of C. pentandra leaves extract better than G. arboreum leaves.


Keyword:     Gossypium arboreum Ceiba pentandra Extract Antipyretic Yeast.


Citation:

Nyi Mekar Saptarini, Dytha Andri Deswati. The Antipyretic Activity of Leaves Extract of Ceiba Pentandra Better than Gossypium arboreum. J App Pharm Sci, 2015; 5 (07): 118-121.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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