Research Article | Volume: 5, Issue: 2, February, 2015

Chemical composition, antimicrobial and antifungal activities of essential oils of the leaves of Aegle marmelos (L.) Correa growing in Egypt

Nabaweya A. Ibrahim,  Fatma S. El-Sakhawy,  Magdy M. D. Mohammed,  Mohamed A. Farid,  Nayera A.M. AbdelWahed,  Doaa A.H. Deabes   
Nabaweya A. Ibrahim1, Fatma S. El-Sakhawy2, Magdy M. D. Mohammed1, Mohamed A. Farid3, Nayera A.M. AbdelWahed3, Doaa A.H. Deabes1

1Pharmacognosy Department, Pharmaceutical and Drug Industries Research Division, National Research Center, Dokki-12311, Cairo, Egypt.

2Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Giza, Egypt.

3Chemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Division, National Research Center, Dokki12311, Cairo, Egypt.

Open Access   

Published:  Feb 27, 2015

DOI: 10.7324/JAPS.2015.50201
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Abstract

The essential oil obtained by hydro-distillation of Aegle marmelos (L.) Correa leaves were analyzed by GC/MS yield (0.9% v/w). Twenty seven components were identified representing 97.76% of the total oil composition. The major components were α-phellenderene (20.97%), α-pinene (17.76%) and δ-carene (16.37%) and other abundant components asγ-cadinene (8.01%), trans-2-hydroxycinnmic acid (6.85%) and β-myrcene (4.32%). The essential oil exhibited significant antibacterial activity against Gram-positive bacteria as Streptococcus faecalis with inhibition zone (30 mm) and Gram-negative bacteria as Pseudomonas aeruginosa (28 mm). Moreover, moderate activity was observed against Bacillus subtilis (23mm), Staphylococcus aureus (23mm), Sarcina lutea (20mm), Arthrobacter citreus (20 mm) and Escherichia coli (25mm) in comparison with antibiotics. The antifungal activity against Aspergillus niger (30 mm) and Candida albicans (30 mm) was higher than the antifungal antibiotics. Moreover, the oil inhibited the germination of Aspergillus niger and Fusarium oxysporum spores at different concentrations.


Keyword:     Aegle marmelos (L.) Correaessentialoilantimicrobial and antifungal activitiesspore germenation.

Citation:

Nabaweya A. Ibrahim, Fatma S. El-Sakhawy, Magdy M. D. Mohammed, Mohamed A. Farid, Nayera A. M. Abdel-Wahed, Doaa A.-H. Deabes. Chemical Composition, Antimicrobial and AntifungalActivities of the Essential Oil ofthe Leaves of Aegle marmelos (L.)Correa Growingin Egypt. J App Pharm Sci, 2015; 5 (02): 001-005.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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