Research Article | Volume: 4, Issue: 2, February, 2014

In vitro antioxidant potential of the essential oil and leaf extracts of Curcuma zedoaria Rosc.

Atiqur Rahman Monira Afroz Rafiquel Islam Kazi Didarul Islam M. Amzad Hossain and Minkyun Na   

Open Access   

Published:  Feb 27, 2014

DOI: 10.7324/JAPS.2014.40217
Abstract

In this study, we examined the chemical composition of the essential oil and tested the antioxidant potential of the oil and leaf extracts of Curcuma zedoaria Rosc. The chemical compositions of the oil were analysed by GC-MS. Twenty-four compounds representing 92.4% of the total oil was identified. The antioxidative potential was evaluated using two separate methods, inhibition of free radical 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and superoxide radicals scavenging activities assay. In the first case, the IC50 value of the oil was 14.8 ± 2.2. Among the extracts, the strongest activity was exhibited by the ethyl acetate extract (IC50 = 17.56 ± 1.6 µg/ml). In the superoxide radicals scavenging activities assay, ethyl acetate extract was superior to all other extracts (IC50 = 23.47 ± 1.2 µg/ml). Furthermore, the amount of total phenolic compounds was also determined as gallic acid equivalent. Thus, the natural products produced from C. zedoaria may be used in food and pharmaceutical industries.


Keyword:     Curcuma zedoaria Rosc essential oilGC-MSantioxidant activities total phenolics.


Citation:

Atiqur Rahman, Monira Afroz, Rafiquel Islam, Kazi Didarul Islam, M. Amzad Hossain and Minkyun Na. In Vitro Antioxidant Potential of the Essential Oil and Leaf Extracts of Curcuma zedoaria Rosc. J App Pharm Sci, 2014; 4 (02): 107-111.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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