Research Article | Volume: 3, Issue: 12, December, 2013

Effects of Ethyl acetate and n-Butanol Fractions of Acacia nilotica methanol Leaves Extract on Lipid profile and Liver Enzyme of Alloxan-Induced Diabetic Wistar rats

Tanko Y.Muhammad A.Emokpae L.V.Mohammed K.A.Jimoh A.Sada N.M Abdulrazak A.Yerima M and Mohammed A   

Open Access   

Published:  Dec 30, 2013

DOI: 10.7324/JAPS.2013.31219
Abstract

This study aimed to evaluate the effects of ethyl acetate and n-butanol fractions of Acacia nilotica methanol leaves extract on lipid profile and liver enzyme on alloxan induced diabetic rats. 30 Wistar rats of both sexes were used for the study. The rats were divided into six groups with five rats in each group. The diabetic rats were treated with n- butanol and ethyl acetate for a period of 12 days. After which the animals were sacrificed and blood serum sample were taken from all the groups for the assessment of lipid profiles and liver enzymes. As regards to the lipid profile there was a significant decrease (P


Keyword:     Ethyl acetaten-butanolliver enzymelipid profilealloxan.


Citation:

Tanko Y., Muhammad A., Emokpae L.V., Mohammed K.A., Jimoh, A., Sada N.M, Abdulrazak A., Yerima M and Mohammed A. Effects of Ethyl acetate and n-Butanol Fractions of Acacia nilotica methanol Leaves Extract on Lipid profile and Liver Enzyme of Alloxan - Induced Diabetic Wistar rats. J App Pharm Sci. 2013; 3 (12): 103-108.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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